{"id":4819,"date":"2025-06-04T07:02:45","date_gmt":"2025-06-04T06:02:45","guid":{"rendered":"https:\/\/cbmeds.in\/?post_type=product&p=4819"},"modified":"2025-06-04T07:02:45","modified_gmt":"2025-06-04T06:02:45","slug":"vitrakvi-capsule-larotrectinib","status":"publish","type":"product","link":"https:\/\/cbmeds.in\/?product=vitrakvi-capsule-larotrectinib","title":{"rendered":"VITRAKVI CAPSULE ( LAROTRECTINIB )"},"content":{"rendered":"

What is VITRAKVI?<\/strong><\/h3>\n

Vitrakvi is used to treat solid tumors in adults and children that are caused by certain abnormal neurotrophic receptor tyrosine kinase (NTRK) genes and the cancer has spread, or surgery to remove the cancer is likely to cause severe complications. Vitrakvi is used when there is no other acceptable treatment option or the solid tumor has grown or spread after other treatments.<\/p>\n

Vitrakvi is an oral capsule or solution that is taken twice a day.<\/p>\n

Vitrakvi (Larotrectinib) is an anti-cancer targeted therapy<\/strong> used to treat:<\/p>\n

\u2705 Solid tumors<\/strong> that have a neurotrophic receptor tyrosine kinase (NTRK) gene fusion<\/strong>
\u2705 When the tumor has no known resistance<\/strong>, and no satisfactory alternative treatment options<\/strong> are available
\u2705 In both adult and pediatric patients<\/strong><\/p>\n

It is not specific to a single cancer type<\/strong>, but rather to the genetic mutation (NTRK fusion<\/strong>) found in many cancers.<\/p>\n

\n

Mechanism of Action:<\/strong><\/h3>\n

Larotrectinib is a selective TRK inhibitor<\/strong>.
It blocks TRK fusion proteins<\/strong>, which are formed when NTRK genes abnormally fuse with other genes and drive tumor growth.<\/p>\n

\n

Common Side Effects:<\/strong><\/h3>\n
    \n
  • \n

    Fatigue<\/p>\n<\/li>\n

  • \n

    Nausea<\/p>\n<\/li>\n

  • \n

    Dizziness<\/p>\n<\/li>\n

  • \n

    Increased liver enzymes<\/p>\n<\/li>\n

  • \n

    Constipation<\/p>\n<\/li>\n

  • \n

    Cough<\/p>\n<\/li>\n

  • \n

    Anemia<\/p>\n<\/li>\n<\/ul>\n

    \n

    Important Notes:<\/strong><\/h3>\n
      \n
    • \n

      Vitrakvi is prescription-only<\/strong> and should be taken under oncologist supervision<\/strong><\/p>\n<\/li>\n

    • \n

      A genetic test<\/strong> is needed to confirm NTRK gene fusion<\/strong> before treatment<\/p>\n<\/li>\n

    • \n

      Dose adjustments may be needed based on liver function and side effects<\/strong><\/p>\n<\/li>\n<\/ul>\n

      \n

      Manufacturer:<\/strong><\/h3>\n

      Bayer<\/strong> (in collaboration with Loxo Oncology)<\/p>\n","protected":false},"excerpt":{"rendered":"

      Brand Name:<\/strong> VITRAKVI<\/h3>\n

      Generic Name:<\/strong> Larotrectinib<\/h3>\n

      Form:<\/strong> Capsule (also available as oral solution)<\/h3>\n

      Available Strengths:<\/strong> 25 mg and 100 mg capsules<\/h3>\n","protected":false},"featured_media":4820,"comment_status":"open","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[34,40,48,31,21,66,39],"product_tag":[],"class_list":{"0":"post-4819","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-breast-cancer","7":"product_cat-colon-cancer","8":"product_cat-kidney-cancer","9":"product_cat-lung-cancer","10":"product_cat-oncology","11":"product_cat-ovarian-cancer","12":"product_cat-prostate-cancer","13":"desktop-align-left","14":"tablet-align-left","15":"mobile-align-left","17":"first","18":"instock","19":"shipping-taxable","20":"product-type-simple"},"yoast_head":"\nVITRAKVI CAPSULE ( LAROTRECTINIB ) - 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