{"id":4856,"date":"2025-06-05T07:02:31","date_gmt":"2025-06-05T06:02:31","guid":{"rendered":"https:\/\/cbmeds.in\/?post_type=product&#038;p=4856"},"modified":"2025-06-05T07:02:32","modified_gmt":"2025-06-05T06:02:32","slug":"lysodren-500-mg-mitotane","status":"publish","type":"product","link":"https:\/\/cbmeds.in\/?product=lysodren-500-mg-mitotane","title":{"rendered":"LYSODREN 500 MG (MITOTANE)"},"content":{"rendered":"<h3 data-start=\"256\" data-end=\"278\">\u2705 <strong data-start=\"262\" data-end=\"276\">Indication<\/strong><\/h3>\n<p data-start=\"279\" data-end=\"402\"><a class=\"crossLinked\" href=\"https:\/\/www.webmd.com\/drugs\/2\/drug-1550\/mitotane-oral\/details\">Mitotane<\/a>\u00a0is used to treat\u00a0<a class=\"crossLinked\" href=\"https:\/\/www.webmd.com\/cancer\/health-check-cancer-risk\/default.htm\">cancer<\/a>\u00a0of the\u00a0<a class=\"crossLinked\" href=\"https:\/\/www.webmd.com\/kidney-stones\/adrenal-glands\">adrenal glands<\/a>. It works by slowing the growth of or killing adrenal gland cells and also decreases the amount of hormones made by the adrenal gland. Used to treat <strong data-start=\"293\" data-end=\"364\">inoperable, metastatic, or recurrent adrenocortical carcinoma (ACC)<\/strong> \u2014 a rare cancer of the adrenal gland.<\/p>\n<hr data-start=\"404\" data-end=\"407\" \/>\n<h3 data-start=\"409\" data-end=\"441\">\u2699\ufe0f <strong data-start=\"416\" data-end=\"439\">Mechanism of Action<\/strong><\/h3>\n<ul data-start=\"442\" data-end=\"603\">\n<li data-start=\"442\" data-end=\"555\">\n<p data-start=\"444\" data-end=\"555\"><strong data-start=\"444\" data-end=\"456\">Mitotane<\/strong> works by <strong data-start=\"466\" data-end=\"501\">destroying adrenal cortex cells<\/strong>, thereby reducing the production of adrenal hormones.<\/p>\n<\/li>\n<li data-start=\"556\" data-end=\"603\">\n<p data-start=\"558\" data-end=\"603\">It has <strong data-start=\"565\" data-end=\"594\">cytotoxic and adrenolytic<\/strong> effects.<\/p>\n<\/li>\n<\/ul>\n<hr data-start=\"605\" data-end=\"608\" \/>\n<h3 data-start=\"610\" data-end=\"653\">\ud83e\uddfe <strong data-start=\"617\" data-end=\"651\">Dosing (Typical Starting Dose)<\/strong><\/h3>\n<ul data-start=\"654\" data-end=\"851\">\n<li data-start=\"654\" data-end=\"759\">\n<p data-start=\"656\" data-end=\"759\"><strong data-start=\"656\" data-end=\"677\">2\u20136 grams per day<\/strong>, divided into 2\u20133 doses (dose is adjusted based on tolerance and blood levels).<\/p>\n<\/li>\n<li data-start=\"760\" data-end=\"851\">\n<p data-start=\"762\" data-end=\"851\"><strong data-start=\"762\" data-end=\"793\">Therapeutic drug monitoring<\/strong> is required to maintain effective mitotane plasma levels.<\/p>\n<\/li>\n<\/ul>\n<hr data-start=\"853\" data-end=\"856\" \/>\n<h3 data-start=\"858\" data-end=\"890\">\u26a0\ufe0f <strong data-start=\"865\" data-end=\"888\">Common Side Effects<\/strong><\/h3>\n<ul data-start=\"891\" data-end=\"1034\">\n<li data-start=\"891\" data-end=\"911\">\n<p data-start=\"893\" data-end=\"911\">Nausea, vomiting<\/p>\n<\/li>\n<li data-start=\"912\" data-end=\"924\">\n<p data-start=\"914\" data-end=\"924\">Diarrhea<\/p>\n<\/li>\n<li data-start=\"925\" data-end=\"936\">\n<p data-start=\"927\" data-end=\"936\">Fatigue<\/p>\n<\/li>\n<li data-start=\"937\" data-end=\"963\">\n<p data-start=\"939\" data-end=\"963\">Dizziness or confusion<\/p>\n<\/li>\n<li data-start=\"964\" data-end=\"979\">\n<p data-start=\"966\" data-end=\"979\">Weight loss<\/p>\n<\/li>\n<li data-start=\"980\" data-end=\"1034\">\n<p data-start=\"982\" data-end=\"1034\">Adrenal insufficiency (requires steroid replacement)<\/p>\n<\/li>\n<\/ul>\n<h2 id=\"warnings\" class=\"ddc-anchor-offset\">Warnings<\/h2>\n<p>You may need to take steroid medicine, or stop taking Lysodren for a short time if you have a serious injury or medical emergency. Your doctor will determine when you can start taking Lysodren again.\u00a0<b>Do not change your doses or medication schedule without advice from your doctor.<\/b><\/p>\n<p><b>You must remain under the care of a doctor while taking Lysodren.<\/b><\/p>\n<p>&nbsp;<\/p>\n<div class=\"title-bg\">\n<h2 class=\"monograph-content-headline\">Precautions<\/h2>\n<\/div>\n<div class=\"monograph-content\">\n<div>\n<p>See also Warning section.<\/p>\n<p class=\"udpated-para-lazy\">Before taking\u00a0<a class=\"crossLinked\" href=\"https:\/\/www.webmd.com\/drugs\/2\/drug-1550\/mitotane-oral\/details\">mitotane<\/a>, tell your doctor or\u00a0<a class=\"crossLinked\" href=\"https:\/\/www.webmd.com\/a-to-z-guides\/features\/pharmacists-they-do-more-than-fill-prescriptions\">pharmacist<\/a>\u00a0if you are allergic to it; or if you have any other\u00a0<a class=\"crossLinked\" href=\"https:\/\/www.webmd.com\/allergies\/allergy-relief-10\/slideshow-allergy-myths-facts\">allergies<\/a>. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.<\/p>\n<p>Before using this\u00a0<a class=\"crossLinked\" href=\"https:\/\/www.webmd.com\/drugs\/index-drugs.aspx\">medication<\/a>, tell your doctor or pharmacist your medical history, especially of:\u00a0<a class=\"crossLinked\" href=\"https:\/\/www.webmd.com\/hepatitis\/liver-and-hepatic-diseases\">liver disease<\/a>,\u00a0<a class=\"crossLinked\" href=\"https:\/\/www.webmd.com\/a-to-z-guides\/understanding-kidney-disease-basic-information\">kidney disease<\/a>, bleeding problems.<\/p>\n<p>Mitotane can make you more likely to get infections or may make current infections worse. Stay away from anyone who has an infection that may easily spread (such as\u00a0<a class=\"crossLinked\" href=\"https:\/\/www.webmd.com\/children\/what-is-chickenpox\">chickenpox<\/a>, COVID-19,\u00a0<a class=\"crossLinked\" href=\"https:\/\/www.webmd.com\/children\/vaccines\/measles-faq\">measles<\/a>,\u00a0<a class=\"crossLinked\" href=\"https:\/\/www.webmd.com\/cold-and-flu\/cold-or-flu-quiz\">flu<\/a>). Talk to your doctor if you have been exposed to an infection or for more details.<\/p>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<h3 data-start=\"48\" data-end=\"87\">\ud83d\udc8a <strong data-start=\"55\" data-end=\"85\">Lysodren (Mitotane 500 mg)<\/strong><\/h3>\n<ul data-start=\"88\" data-end=\"249\">\n<li data-start=\"88\" data-end=\"118\">\n<p data-start=\"90\" data-end=\"118\"><strong data-start=\"90\" data-end=\"106\">Generic Name<\/strong>: Mitotane<\/p>\n<\/li>\n<li data-start=\"119\" data-end=\"151\">\n<p data-start=\"121\" data-end=\"151\"><strong data-start=\"121\" data-end=\"135\">Brand Name<\/strong>: <strong data-start=\"137\" data-end=\"149\">Lysodren<\/strong><\/p>\n<\/li>\n<li data-start=\"152\" data-end=\"196\">\n<p data-start=\"154\" data-end=\"196\"><strong data-start=\"154\" data-end=\"170\">Manufacturer<\/strong>: <strong data-start=\"172\" data-end=\"194\">HRA Pharma, France<\/strong><\/p>\n<\/li>\n<li data-start=\"197\" data-end=\"222\">\n<p data-start=\"199\" data-end=\"222\"><strong data-start=\"199\" data-end=\"207\">Form<\/strong>: Oral tablet<\/p>\n<\/li>\n<li data-start=\"223\" data-end=\"249\">\n<p data-start=\"225\" data-end=\"249\"><strong data-start=\"225\" data-end=\"237\">Strength<\/strong>: <strong data-start=\"239\" data-end=\"249\">500 mg<\/strong><\/p>\n<\/li>\n<\/ul>\n","protected":false},"featured_media":4857,"comment_status":"open","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[83],"product_tag":[],"class_list":{"0":"post-4856","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-adrenal-glands-cancer","7":"desktop-align-left","8":"tablet-align-left","9":"mobile-align-left","11":"first","12":"instock","13":"shipping-taxable","14":"product-type-simple"},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.5 - 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