Indications<\/strong>:<\/h3>\n <\/p>\n
\u00a0 \u00a0 \u00a0 \u00a0Alunbrig<\/strong> is indicated for:<\/p>\n\n- \n
Treatment of adult patients<\/strong> with anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC)<\/strong><\/p>\n<\/li>\n- \n
ALK positivity must be confirmed using an FDA-approved diagnostic test<\/strong><\/p>\n<\/li>\n- \n
Especially used in patients who have:<\/p>\n
\n- \n
Progressed on crizotinib<\/strong><\/p>\n<\/li>\n- \n
Or are intolerant to crizotinib<\/strong><\/p>\n<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n
\n\ud83d\udd38 Mechanism of Action<\/strong>:<\/h3>\n <\/p>\n
\u00a0 \u00a0 \u00a0 \u00a0 Brigatinib is a tyrosine kinase inhibitor (TKI)<\/strong> that targets ALK gene rearrangements, which are drivers in a subset of NSCLC cases.<\/p>\n
\n\ud83d\udd38 Dosing Strategy<\/strong>:<\/h3>\n <\/p>\n
\n- \n
Initial Dose<\/strong>: 90 mg once daily<\/strong> for the first 7 days<\/strong><\/p>\n<\/li>\n- \n
Maintenance Dose<\/strong>: Increase to 180 mg once daily<\/strong> if tolerated
\n<\/p>\n<\/li>\n<\/ul>\n
\n\ud83d\udd38 Common Side Effects<\/strong>:<\/h3>\n <\/p>\n
\n- \n
Nausea, fatigue, diarrhea<\/p>\n<\/li>\n
- \n
Increased blood pressure (hypertension)<\/p>\n<\/li>\n
- \n
Cough, shortness of breath<\/p>\n<\/li>\n
- \n
Visual disturbances<\/p>\n<\/li>\n
- \n
Elevated liver enzymes (ALT\/AST)<\/p>\n<\/li>\n<\/ul>\n
\n\u26a0\ufe0f Serious Warnings \/ Precautions<\/strong>:<\/h3>\n <\/p>\n
\n- \n
Pulmonary toxicity<\/strong><\/p>\n<\/li>\n- \n
Hypertension<\/strong><\/p>\n<\/li>\n- \n
Bradycardia<\/strong><\/p>\n<\/li>\n- \n
Visual disturbances<\/strong><\/p>\n<\/li>\n- \n
Hyperglycemia<\/strong><\/p>\n<\/li>\n- \n
Creatine phosphokinase (CPK) elevation<\/strong><\/p>\n<\/li>\n- \n
Hepatotoxicity<\/strong><\/p>\n<\/li>\n<\/ul>\n
\n\ud83d\udd38 Monitoring Parameters<\/strong>:<\/h3>\n <\/p>\n
\n- \n
Liver function tests<\/p>\n<\/li>\n
- \n
Blood pressure<\/p>\n<\/li>\n
- \n
Heart rate (ECG if symptomatic)<\/p>\n<\/li>\n
- \n
Glucose levels<\/p>\n<\/li>\n
- \n
Pulmonary symptoms in early days<\/p>\n<\/li>\n<\/ul>\n
\n\u2705 Conclusion<\/strong>:<\/h3>\n <\/p>\n
Alunbrig (brigatinib)<\/strong> is a potent next-generation ALK inhibitor for ALK+ NSCLC<\/strong>, especially effective after failure or intolerance to crizotinib<\/strong>. Its staged dosing strategy and strong efficacy profile make it a critical option in the treatment pathway for these patients, but it requires careful monitoring for adverse effects\u2014especially early-onset lung complications.<\/p>\n","protected":false},"excerpt":{"rendered":"\ud83d\udccc Key Details<\/strong><\/h3>\n <\/p>\n
\n- \n
Brand Name<\/strong>: Alunbrig<\/span><\/p>\n<\/li>\n- \n
Generic Name (Salt)<\/strong>: Brigatinib<\/span><\/p>\n<\/li>\n- \n
Manufacturer<\/strong>: Takeda Pharmaceuticals<\/span><\/p>\n<\/li>\n- \n
Formulation<\/strong>: Oral tablets<\/span><\/p>\n<\/li>\n- \n
Available Strengths<\/strong>: 30 mg, 90 mg, and 180 mg<\/span><\/p>\n<\/li>\n- \n
Indications<\/strong>:<\/p>\n\n- \n
Treatment of adult patients with anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC) as detected by an FDA-approved test.<\/span><\/p>\n<\/li>\n- \n
Approved for patients who have progressed on or are intolerant to crizotinib.<\/span><\/p>\n<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n","protected":false},"featured_media":4935,"comment_status":"open","ping_status":"closed","template":"","meta":{"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"default","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"var(--ast-global-color-4)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}}},"product_brand":[],"product_cat":[31],"product_tag":[],"class_list":{"0":"post-4934","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-lung-cancer","7":"desktop-align-left","8":"tablet-align-left","9":"mobile-align-left","11":"first","12":"instock","13":"shipping-taxable","14":"product-type-simple"},"yoast_head":"\nALUNBRIG 90MG\/ 180MG TAB (BRIGATINIB) - Curiance Biotech<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/cbmeds.in\/?product=alunbrig-90mg-180mg-tab-brigatinib\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"ALUNBRIG 90MG\/ 180MG TAB (BRIGATINIB) - Curiance Biotech\" \/>\n<meta property=\"og:description\" content=\"\ud83d\udccc Key Details Brand Name: Alunbrig Generic Name (Salt): Brigatinib Manufacturer: Takeda Pharmaceuticals Formulation: Oral tablets Available Strengths: 30 mg, 90 mg, and 180 mg Indications: Treatment of adult patients with anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC) as detected by an FDA-approved test. 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