XPOVIO 40MG /80MG TAB ( SELINEXOR )

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Important Guide

  • Brand Name: Xpovio

  • Generic Name: Selinexor

  • Strengths: 20 mg and 80 mg tablets
  • Manufacturer: Karyopharm Therapeutics Inc. (USA)

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Country of Origin

India

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DISEASE INDICATIONS

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FREQUENTLY ASKED QUESTIONS

Payments can be made by credit card or bank transfer. Payments are fully encrypted and secure. When paying by credit card, you can pay online once you have received your order confirmation. Please be aware that a 2.8% fee applies when paying by credit card.
 
Payments can be made by credit card or bank transfer. Payments are fully encrypted and secure. When paying by credit card, you can pay online once you have received your order confirmation. Please be aware that a 2.8% fee applies when paying by credit card.
 
Payments can be made by credit card or bank transfer. Payments are fully encrypted and secure. When paying by credit card, you can pay online once you have received your order confirmation. Please be aware that a 2.8% fee applies when paying by credit card.
 
Payments can be made by credit card or bank transfer. Payments are fully encrypted and secure. When paying by credit card, you can pay online once you have received your order confirmation. Please be aware that a 2.8% fee applies when paying by credit card.
 
Payments can be made by credit card or bank transfer. Payments are fully encrypted and secure. When paying by credit card, you can pay online once you have received your order confirmation. Please be aware that a 2.8% fee applies when paying by credit card.
 

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Dr. Akshi Sudan

Patient Support Team Lead

Dr. Akshi Sudan

Patient Support Team Lead

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What is Xpovio?

Xpovio is used to treat multiple myeloma (MM) or relapsed/refractory diffuse large B-cell lymphoma (DLBCL) in adults. Xpovio is an oral tablet that is taken 1 to 2 times a week. Xpovio (selinexor) gained FDA approval on July 3, 2019. There is no generic . Xpovio (selinexor) is a nuclear export inhibitor indicated in combination with dexamethasone for the treatment of adult patients with relapsed or refractory multiple myeloma (RRMM) who have received at least four prior therapies and whose disease is refractory to at least two proteasome inhibitors, at least two immunomodulatory agents, and an anti-CD38 monoclonal antibody.

What Are Side Effects of Xpovio?

Xpovio may cause serious side effects including:

  • hives,
  • difficulty breathing,
  • swelling of your face, lips, tongue, or throat,
  • severe ongoing nausea,
  • vomiting,
  • diarrhea,
  • loss of appetite,
  • weight loss,
  • confusion,
  • dizziness,
  • fainting,
  • changes in mental status,
  • easy bruising,
  • unusual bleeding,
  • purple or red spots under the skin,
  • fever,
  • chills,
  • flu symptoms,
  • cough with mucus,
  • mouth and throat ulcers,
  • rapid heart rate,
  • shortness of breath,
  • tingly or painful blistering rash on one side of your body,
  • pale skin,
  • unusual tiredness,
  • lightheadedness,
  • cold hands and feet,
  • headache,
  • confusion,
  • slurred speech,
  • severe weakness,
  • loss of coordination, and
  • feeling unsteady

Get medical help right away, if you have any of the symptoms listed above.

Common side effects of Xpovio include:

  • low blood platelets,
  • fatigue,
  • nausea,
  • anemia,
  • decreased appetite,
  • weight loss,
  • diarrhea,
  • vomiting,
  • low blood sodium,
  • low white blood cell counts,
  • constipation,
  • shortness of breath, and
  • upper respiratory tract infection

⚠️ Important Considerations

  • Prescription Requirement: Xpovio is a prescription-only medication. Ensure you have a valid prescription from an oncologist or qualified healthcare provider.

  • Side Effects: Common side effects include nausea, fatigue, decreased appetite, and low blood counts. Regular monitoring by a healthcare professional is essential during treatment.

  • Storage: Store the tablets at room temperature, away from moisture and heat.

📋 Dosage Guidelines

The dosing of Selinexor varies based on the specific condition:

  • Multiple Myeloma: 80 mg taken orally once weekly, in combination with dexamethasone.

  • DLBCL: 60 mg taken orally twice weekly.

This content has been reviewed by a Medical Doctor.
 

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Since we help patients access medicines not available in their home country, our first step is to check that the medicine you need is not currently available in your home country. Next we will also verify that you have a prescription from a doctor in your home country for the medicine you need.

Once we have verified your prescription and medical details, our expert sourcing team will work with our global network of suppliers to find you the best price. Once we have found you the lowest possible cost for your medicine, we will present you with a final offer for your approval.

 
This content has been reviewed by a Medical Doctor.