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ATTRUBY (ACORAMIDIS 356 MG )

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Important Guide

Acoramidis is an oral transthyretin (TTR) stabilizer indicated for the treatment of transthyretin amyloid cardiomyopathy (ATTR-CM). It works by preventing the formation of amyloid deposits in the heart, helping to slow disease progression, preserve cardiac function, and reduce cardiovascular events.

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Category TRANSTHYRETIN AMYLOID CARDIOMYOPATHY

Country of Origin

India

MEDICINE APPROVED BY

DISEASE INDICATIONS

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🏷️ Brand Name

Attruby

🧪 Generic Name (Salt)

Acoramidis

🏭 Manufacturer

BridgeBio Pharma

💊 Strength

356 mg Tablets

📋 Class

Transthyretin (TTR) Stabilizer

🎯 Indication / Usage

Treatment of Transthyretin Amyloid Cardiomyopathy (ATTR-CM)
Used in adults with wild-type or hereditary ATTR-CM
Helps reduce cardiovascular complications and disease progression

⚙️ Mechanism of Action

Binds to and stabilizes the transthyretin (TTR) protein
Prevents TTR from dissociating and forming amyloid deposits
Helps protect heart function

💉 Dosage

712 mg twice daily (two 356 mg tablets per dose)
Oral administration with or without food

⚠️ Common Side Effects

Diarrhea
Upper abdominal pain
Mild gastrointestinal disturbances

🚨 Precautions

Use under specialist supervision
Monitor cardiac status regularly
Inform physician about all concomitant medications
Safety in pregnancy and breastfeeding has not been established

This content has been reviewed by a Medical Doctor.

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