LUMAKRAS 120 MG TABLET (SOTORASIB)

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Brand Name: Lumakras

Generic Name: Sotorasib

Strengths: 120 mg tablet

Form: Oral tablet

Manufacturer: Amgen

Product Meta

Category

Country of Origin

India

MEDICINE APPROVED BY

DISEASE INDICATIONS

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FREQUENTLY ASKED QUESTIONS

Payments can be made by credit card or bank transfer. Payments are fully encrypted and secure. When paying by credit card, you can pay online once you have received your order confirmation. Please be aware that a 2.8% fee applies when paying by credit card.
 
Payments can be made by credit card or bank transfer. Payments are fully encrypted and secure. When paying by credit card, you can pay online once you have received your order confirmation. Please be aware that a 2.8% fee applies when paying by credit card.
 
Payments can be made by credit card or bank transfer. Payments are fully encrypted and secure. When paying by credit card, you can pay online once you have received your order confirmation. Please be aware that a 2.8% fee applies when paying by credit card.
 
Payments can be made by credit card or bank transfer. Payments are fully encrypted and secure. When paying by credit card, you can pay online once you have received your order confirmation. Please be aware that a 2.8% fee applies when paying by credit card.
 
Payments can be made by credit card or bank transfer. Payments are fully encrypted and secure. When paying by credit card, you can pay online once you have received your order confirmation. Please be aware that a 2.8% fee applies when paying by credit card.
 

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Our Patient Support Team will personally assist you along the way

Dr. Akshi Sudan

Patient Support Team Lead

Dr. Akshi Sudan

Patient Support Team Lead

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What is LUMAKRAS Used For?

Lumakras is used to treat:

Non-Small Cell Lung Cancer (NSCLC)
✅ In adults with KRAS G12C mutation-positive tumors
✅ Typically used after at least one prior systemic therapy

What are the ingredients in Lumakras?

Active Ingredient: sotorasib

Inactive Ingredients: microcrystalline cellulose, lactose monohydrate, croscarmellose sodium, and magnesium stearate. Tablet film coating material contains polyvinyl alcohol, titanium dioxide, polyethylene glycol, talc, iron oxide yellow and iron oxide red (320 mg tablet only).


Mechanism of Action:

Sotorasib is a KRAS G12C inhibitor.
It selectively and irreversibly binds to the mutant KRAS G12C protein, inhibiting its signaling and stopping cancer cell growth.


Key Requirements:

  • KRAS G12C mutation must be confirmed by an FDA-approved test

  • Not effective in patients without this specific mutation


Common Side Effects:

  • Diarrhea

  • Nausea

  • Elevated liver enzymes

  • Fatigue

  • Joint pain

  • Cough

 


Warnings & Monitoring:

  • Liver function should be regularly monitored

  • Possible risk of interstitial lung disease (ILD)/pneumonitis

  • Dose adjustments may be needed based on side effects

This content has been reviewed by a Medical Doctor.
 

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This content has been reviewed by a Medical Doctor.