LYSODREN 500 MG (MITOTANE)

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Important Guide

šŸ’Š Lysodren (Mitotane 500 mg)

  • Generic Name: Mitotane

  • Brand Name: Lysodren

  • Manufacturer: HRA Pharma, France

  • Form: Oral tablet

  • Strength: 500 mg

Product Meta

Country of Origin

India

MEDICINE APPROVED BY

DISEASE INDICATIONS

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FREQUENTLY ASKED QUESTIONS

Payments can be made by credit card or bank transfer. Payments are fully encrypted and secure. When paying by credit card, you can pay online once you have received your order confirmation. Please be aware that a 2.8% fee applies when paying by credit card.
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Payments can be made by credit card or bank transfer. Payments are fully encrypted and secure. When paying by credit card, you can pay online once you have received your order confirmation. Please be aware that a 2.8% fee applies when paying by credit card.
Ā 
Payments can be made by credit card or bank transfer. Payments are fully encrypted and secure. When paying by credit card, you can pay online once you have received your order confirmation. Please be aware that a 2.8% fee applies when paying by credit card.
Ā 
Payments can be made by credit card or bank transfer. Payments are fully encrypted and secure. When paying by credit card, you can pay online once you have received your order confirmation. Please be aware that a 2.8% fee applies when paying by credit card.
Ā 
Payments can be made by credit card or bank transfer. Payments are fully encrypted and secure. When paying by credit card, you can pay online once you have received your order confirmation. Please be aware that a 2.8% fee applies when paying by credit card.
Ā 

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Dr. Akshi Sudan

Patient Support Team Lead

Dr. Akshi Sudan

Patient Support Team Lead

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āœ… Indication

MitotaneĀ is used to treatĀ cancerĀ of theĀ adrenal glands. It works by slowing the growth of or killing adrenal gland cells and also decreases the amount of hormones made by the adrenal gland. Used to treat inoperable, metastatic, or recurrent adrenocortical carcinoma (ACC) — a rare cancer of the adrenal gland.


āš™ļø Mechanism of Action

  • Mitotane works by destroying adrenal cortex cells, thereby reducing the production of adrenal hormones.

  • It has cytotoxic and adrenolytic effects.


🧾 Dosing (Typical Starting Dose)

  • 2–6 grams per day, divided into 2–3 doses (dose is adjusted based on tolerance and blood levels).

  • Therapeutic drug monitoring is required to maintain effective mitotane plasma levels.


āš ļø Common Side Effects

  • Nausea, vomiting

  • Diarrhea

  • Fatigue

  • Dizziness or confusion

  • Weight loss

  • Adrenal insufficiency (requires steroid replacement)

Warnings

You may need to take steroid medicine, or stop taking Lysodren for a short time if you have a serious injury or medical emergency. Your doctor will determine when you can start taking Lysodren again.Ā Do not change your doses or medication schedule without advice from your doctor.

You must remain under the care of a doctor while taking Lysodren.

 

Precautions

See also Warning section.

Before takingĀ mitotane, tell your doctor orĀ pharmacistĀ if you are allergic to it; or if you have any otherĀ allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.

Before using thisĀ medication, tell your doctor or pharmacist your medical history, especially of:Ā liver disease,Ā kidney disease, bleeding problems.

Mitotane can make you more likely to get infections or may make current infections worse. Stay away from anyone who has an infection that may easily spread (such asĀ chickenpox, COVID-19,Ā measles,Ā flu). Talk to your doctor if you have been exposed to an infection or for more details.

This content has been reviewed by a Medical Doctor.
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This content has been reviewed by a Medical Doctor.