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REVUFORJ (REVUMENIB 110MG /160 MG)

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Important Guide

Revumenib is an oral menin inhibitor indicated for the treatment of relapsed or refractory acute leukemia with KMT2A rearrangement. It works by disrupting the menin-KMT2A protein interaction that drives leukemia growth, helping leukemia cells mature into normal blood cells and slowing disease progression.

Product Meta

Category Leukemia

Country of Origin

India

MEDICINE APPROVED BY

DISEASE INDICATIONS

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🏷️ Brand Name

Revuforj

🧪 Generic Name (Salt)

Revumenib

🏭 Manufacturer

Syndax Pharmaceuticals

💊 Strengths

110 mg & 160 mg Tablets

📋 Class

Menin Inhibitor

🎯 Indication / Usage

Treatment of Relapsed or Refractory Acute Leukemia with KMT2A (MLL) rearrangement
Used in patients with specific genetic alterations driving leukemia

⚙️ Mechanism of Action

Inhibits the menin-KMT2A interaction
Blocks leukemia cell growth and survival
Promotes differentiation of leukemic cells into normal blood cells

💉 Dosage

Oral administration
Dose and schedule depend on concomitant medications and physician recommendation

⚠️ Common Side Effects

Nausea
Vomiting
Fatigue
Constipation
Edema (swelling)
Fever

🚨 Precautions

Monitor ECG for QT interval prolongation
Regular liver function and blood count monitoring required
Monitor for Differentiation Syndrome
Inform physician about all concomitant medications due to potential drug interactions

This content has been reviewed by a Medical Doctor.

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